Research

St Vincent’s Hospital Inflammatory Bowel Disease Service are dedicated to ongoing research and education. We supervise and educate medical students and PhD students and engage in many research projects that cover all aspects of IBD, including:

  • bone health
  • medication optimisation
  • utilising new and novel ways to track disease
  • the role of dietary interventions
  • and investigating new therapies.

We also collaborate with other researchers within our hospital, university as well as to larger research networks across Australia.

Selected publications

Pudipeddi A, Paramsothy S, Kariyawasam V, Paramsothy R, Ghaly S, Haifer C, An YK, Begun J, Connor SJ, Corte C, Ward MG, De Cruz P, Lan-San Fung C, Redmond D, Chan W, Mourad F, Kermeen M, Leong RW. Effects of Thiopurine Withdrawal on Vedolizumab-Treated Patients With Ulcerative Colitis: A Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2024 May 9:S1542-3565(24)00426-9.

Haifer C, Paramsothy S, Kaakoush NO, Saikal A, Ghaly S, Yang T, Luu LDW, Borody TJ, Leong RW. Lyophilised oral faecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial. Lancet Gastroenterol Hepatol. 2022 Feb;7(2):141-151. doi: 10.1016/S2468-1253(21)00400-3. Epub 2021 Dec 2

Haifer C, Srinivasan A, An YK, Picardo S, van Langenberg D, Menon S, Begun J, Ghaly S, Thin L. Switching Australian patients with moderate to severe inflammatory bowel disease from originator to biosimilar infliximab: a multicentre, parallel cohort study. Med J Aust. 2021 Feb;214(3):128-133. doi: 10.5694/mja2.50824. Epub 2020 Oct 17. PMID: 33070332.   

Katsoudas N, Tavakoli P, Wu N, Shapiro A, Leach ST, Williams AJ, Paramsothy R, Ghaly S, Connor SJ, Samocha-Bonet D, Lambert K, Hold GL. Dietary Emulsifier Exposure in People With Inflammatory Bowel Disease Compared With Healthy Controls: Is There a Cause for Concern? Inflamm Bowel Dis. 2024 Jan 19:izad318. doi: 10.1093/ibd/izad318.

Wark G, Samocha-Bonet D, Ghaly S, Danta M. The Role of Diet in the Pathogenesis and Management of Inflammatory Bowel Disease: A Review. Nutrients. 2020 Dec 31;13(1):135. doi: 10.3390/nu13010135. PMID: 33396537; PMCID: PMC7823614.

Kim AH, Girgis A, Karimi N, Sechi AJ, Descallar J, Andrews JM, Siegel CA, Connor SJ. A Web-Based Decision Aid (myAID) to Enhance Quality of Life, Empowerment, Decision Making, and Disease Control for Patients With Ulcerative Colitis: Protocol for a Cluster Randomized Controlled Trial. JMIR Res Protoc. 2020 Jul 10;9(7):e15994. doi: 10.2196/15994. PMID: 32673257; PMCID: PMC7382012.

Haifer C, Leong RW, Paramsothy S. The role of faecal microbiota transplantation in the treatment of inflammatory bowel disease. Curr Opin Pharmacol. 2020 Dec;55:8-16. doi: 10.1016/j.coph.2020.08.009. Epub 2020 Oct 7. PMID: 33035780; PMCID: PMC7538387.